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Effects of venlafaxine in the sleep architecture of rats.

作者信息

Salin-Pascual R J, Moro-Lopez M L

机构信息

Departamento de Fisiologia, Facultad de Medicina, Universidad Nacional Autonoma de Mexico, Mexico City, Mexico.

出版信息

Psychopharmacology (Berl). 1997 Feb;129(3):295-6. doi: 10.1007/s002130050194.

Abstract

Different venlafaxine doses (1, 5, and 10 mg/kg) and saline solution were administered to ten male Wistar rats (Latin-Square design). Compared with saline, venlafaxine produced a dose-related suppression of REM sleep and an increase in wake time while slow wave sleep was reduced. This effect is similar to the one that has been reported with some tricyclic antidepressants.

摘要

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