Salisbury P L, Caloss R, Cruz J M, Powell B L, Cole R, Kohut R I
Department of Dentistry, Bowman Gray School of Medicine, Winston-Salem, N.C., USA.
Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 1997 Mar;83(3):340-4. doi: 10.1016/s1079-2104(97)90240-7.
Mucormycosis is a fulminant fungal infection that occurs most often in diabetic and immunocompromised patients including those with hematologic malignancies. In this case, a patient with acute myelogenous leukemia developed mucormycosis in a recent mandibular extraction site. The successful management of this patient demonstrated that early diagnosis, aggressive surgical and medical treatment and resolution of the underlying disease could improve the prognosis for survival. A case is made for the role of smoking as an initiator of mucormycosis, and treatment considerations for controlling periodontal and pulpal disease before chemotherapy are discussed.
毛霉菌病是一种暴发性真菌感染，最常发生于糖尿病患者和免疫功能低下患者，包括血液系统恶性肿瘤患者。在本病例中，一名急性髓性白血病患者在近期下颌拔牙部位发生了毛霉菌病。该患者的成功治疗表明，早期诊断、积极的手术和药物治疗以及潜在疾病的解决可改善生存预后。本文探讨了吸烟作为毛霉菌病诱因的作用，以及化疗前控制牙周和牙髓疾病的治疗注意事项。
