Fingeroth J D, Roth R S, Talcott J A, Rinaldi M G
Laboratory of Infectious Diseases, Dana-Farber Cancer Institute, Boston, Massachusetts 02115.
Clin Infect Dis. 1994 Jul;19(1):135-7. doi: 10.1093/clinids/19.1.135.
Mucor circinelloides form circinelloides has rarely been associated with human disease, even in immunocompromised patients. We report a case of cutaneous zygomycosis caused by M. circinelloides in a 23-year-old neutropenic woman receiving consolidation chemotherapy for acute myelogenous leukemia. The organism was exquisitely susceptible to amphotericin B. Despite the fact that the patient was profoundly neutropenic for an additional 3 weeks, the lesions began to resolve during therapy, and no surgical debridement was required.
卷枝毛霉很少与人类疾病相关,即使在免疫功能低下的患者中也是如此。我们报告了一例由卷枝毛霉引起的皮肤接合菌病,患者为一名23岁的中性粒细胞减少女性,正在接受急性髓性白血病巩固化疗。该菌对两性霉素B极为敏感。尽管患者在接下来的3周内仍严重中性粒细胞减少,但病变在治疗期间开始消退,无需手术清创。