Martinot V, Descamps S, Février P, Patenotre P, Brevière J M, Piette F, Pellerin P
Service de chirurgie plastique, hôpital Roger-Salengro, Lille, France.
Arch Pediatr. 1997 Jan;4(1):8-14. doi: 10.1016/s0929-693x(97)84296-0.
Surgical treatment of cystic lymphangioma (CL) is so often followed by local and general complications that non invasive treatment must be considered.
Between 1987 and 1993, 20 patients with a superficial macrocystic lymphangioma were treated by percutaneous injection of Ethibloc in order to reduce the volume of the CL, with a minimum follow-up of 1 year. Fourteen CL were cervico-facial and six were located in the upper half of the body. The size of the lesion was determined by echography: three CL were less than 5 cm in diameter, 12 between 5 and 10 cm, five more than 10 cm. Two to 5 mL of Ethibloc were injected during one (15 cases) or several sessions (five cases).
Reduction in volume was excellent in 12 patients after one session and in four patients after several sessions. Four patients had a poor result. All the patients suffered from an important inflammatory reaction for 2 or 3 days followed by exteriorisation of the Ethibloc in seven patients, with a discrete final scar.
These fair results suggest that intracystic injection of Ethibloc represents an effective alternative to surgery.
囊性淋巴管瘤(CL)的手术治疗常常伴随着局部和全身并发症,因此必须考虑非侵入性治疗。
1987年至1993年间,20例浅表性大囊型淋巴管瘤患者接受了经皮注射Ethibloc治疗,以缩小CL的体积,最短随访时间为1年。14例CL位于颈面部,6例位于身体上半部分。通过超声检查确定病变大小:3例CL直径小于5 cm,12例在5至10 cm之间,5例大于10 cm。在一次(15例)或多次(5例)治疗过程中注射2至5 mL的Ethibloc。
12例患者在一次治疗后体积缩小效果极佳,4例患者在多次治疗后效果良好。4例患者效果不佳。所有患者均出现了持续2至3天的严重炎症反应,7例患者随后出现Ethibloc排出,最终留下轻微疤痕。
这些尚可的结果表明,囊内注射Ethibloc是一种有效的手术替代方法。