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动脉瘤样骨囊肿:直接经皮注射乙碘油治疗:长期结果

Aneurysmal bone cysts: treatment with direct percutaneous Ethibloc injection: long-term results.

作者信息

Falappa Piergiorgio, Fassari Fausto M, Fanelli Arturo, Genovese Elisabetta, Ascani Elio, Crostelli Marco, Salsano Vittorio, Montanaro Antonello, Di Lazzaro Antonio, Serra Fabrizio

机构信息

Department of Radiology, Hospital IDI IRCCS, Via Monti di Creta, 104, I-00167 Rome, Italy.

出版信息

Cardiovasc Intervent Radiol. 2002 Jul-Aug;25(4):282-90. doi: 10.1007/s00270-001-0062-2. Epub 2002 May 20.

Abstract

PURPOSE

To assess the efficacy and long-term results of Ethibloc treatment in aneurysmal bone cysts (ABC).

METHODS

Thirteen patients with ABC were treated with direct percutaneous Ethibloc injection. Four patients had only one injection and the other nine patients from two to four injections. No severe complications were observed; in two patients a local leakage of Ethibloc from the cyst into the soft tissues occurred but it was temporary and the consequent inflammation self-healed without residua and sequelae. Imaging follow-up lasted from 6 to 67 months and included conventional radiology (CR) and magnetic resonance imaging (MRI), both used in the presurgical phase.

RESULTS AND CONCLUSIONS

All images demonstrated a remarkable shrinkage of the cystic lesion and bone cortex thickening. In all patients, circumscribed areas of lucency persisted at radiography, corresponding to residual cystic areas without fluid-fluid levels at MRI. Pain, which was present in all the patients before treatment, was relieved within a month. According to our experience, direct percutaneous Ethibloc injection is effective in the treatment of ABC and can be recommended as the first-choice treatment. Due to its higher sensitivity MRI must be included either in the pretreatment phase to study the multilocular structure or in the imaging follow-up to evaluate the efficacy of Ethibloc in persistently non-responsive areas.

摘要

目的

评估Ethibloc治疗骨囊肿(ABC)的疗效和长期结果。

方法

13例ABC患者接受了经皮直接Ethibloc注射治疗。4例患者仅注射1次,其他9例患者注射2至4次。未观察到严重并发症;2例患者出现Ethibloc从囊肿局部渗漏至软组织,但为暂时性,随后的炎症自行愈合,无残留和后遗症。影像学随访持续6至67个月,包括术前阶段使用的传统放射学(CR)和磁共振成像(MRI)。

结果与结论

所有图像均显示囊性病变明显缩小,骨皮质增厚。所有患者在放射学检查中均有局限性透亮区持续存在,对应于MRI上无液-液平面的残留囊性区域。所有患者治疗前均存在的疼痛在1个月内缓解。根据我们的经验,经皮直接Ethibloc注射治疗ABC有效,可推荐作为首选治疗方法。由于MRI具有较高的敏感性,必须在治疗前阶段用于研究多房结构,或在影像学随访中用于评估Ethibloc在持续无反应区域的疗效。

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