George Harvey L, Unnikrishnan Puthanveettil Nithin, Garg Neeraj K, Sampath Jayanth Sundar, Bass Alf, Bruce Colin E
Department of Orthopaedics, Alder Hey Children's Hospital, Liverpool, UK.
J Pediatr Orthop B. 2009 Nov;18(6):375-80. doi: 10.1097/BPB.0b013e32832f724c.
The aim of this study is to assess the long-term results of Ethibloc injection in aneurysmal bone cysts (ABC). Thirty-three patients with ABC were treated with computed tomography-guided percutaneous injection of Ethibloc into the cyst cavity. Twenty-two patients had Ethibloc injection as primary treatment and 11 patients had presented to us with recurrence after previous procedures including steroid injection, bone marrow injection, curettage bone grafting and various other surgical procedures. The mean follow-up was 54 (22-90) months. Symptoms were relieved in all patients. Two patients were lost to follow-up. Eighteen (58%) of the 31 patients followed, had complete resolution of the lesion, 11 (35.5%) patients had partial healing (asymptomatic residual nonprogressive lytic areas). Two (6.5%) patients showed recurrence in the proximal humerus during the follow-up. They are under follow-up but asymptomatic and another two patients encountered more significant complications after the procedure. Ethibloc injection is a relatively simple, minimally invasive alternative procedure for the treatment of ABC, and makes open operation unnecessary by stopping the expansion of the cyst and inducing endosteal new bone formation. This technique may be used as the primary management of ABC's excluding spinal lesions as shown by our largest and longest follow-up study.
本研究的目的是评估乙碘油注射治疗骨囊肿（ABC）的长期效果。33例ABC患者接受了计算机断层扫描引导下经皮向囊肿腔内注射乙碘油治疗。22例患者将乙碘油注射作为主要治疗方法，11例患者在先前接受包括类固醇注射、骨髓注射、刮除植骨及其他各种外科手术等治疗后复发。平均随访时间为54（22 - 90）个月。所有患者症状均得到缓解。2例患者失访。在接受随访的31例患者中，18例（58%）病变完全消退，11例（35.5%）患者部分愈合（无症状的残留非进行性溶骨区）。2例（6.5%）患者在随访期间肱骨近端出现复发。他们仍在接受随访，但无症状，另外2例患者在术后出现了更严重的并发症。乙碘油注射是一种相对简单、微创的ABC治疗替代方法，通过阻止囊肿扩大并诱导骨内膜新骨形成，无需进行开放手术。如我们最大规模且最长时间的随访研究所显示，该技术可作为ABC（不包括脊柱病变）的主要治疗方法。
