La M, Paisley K, Martin W, Rand M J
Department of Medical Laboratory Science, Royal Melbourne Institute of Technology, Victoria, Australia.
Eur J Pharmacol. 1997 Mar 5;321(3):R5-6. doi: 10.1016/s0014-2999(97)00048-4.
Hydroxocobalamin inhibited nitrergic nerve-induced relaxations in rat anococcygeus and bovine retractor penis muscles in a concentration-dependent manner. In the rat anococcygeus muscle, the inhibition was greater in light than in dark conditions, whereas in the bovine retractor penis the inhibition was similar under both conditions.
羟钴胺素以浓度依赖性方式抑制大鼠肛门尾骨肌和牛阴茎退缩肌中一氧化氮能神经诱导的舒张。在大鼠肛门尾骨肌中,光照条件下的抑制作用比黑暗条件下更强,而在牛阴茎退缩肌中,两种条件下的抑制作用相似。