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1973 - 1994年瑞士性传播疾病监测:淋病和梅毒呈下降趋势的证据

Surveillance of sexually transmitted diseases in Switzerland, 1973-1994: evidence of declining trends in gonorrhoea and syphilis.

作者信息

Paget W J, Zimmermann H P

机构信息

Swiss Federal Office of Public Health, Division of Epidemiology and Infectious Diseases, Liebefeld-Bern.

出版信息

Soz Praventivmed. 1997;42(1):30-6. doi: 10.1007/BF01299576.

Abstract

The HIV/AIDS epidemic has led to growing interest in the epidemiology of sexually transmitted diseases (STDs) in Switzerland. STD surveillance data from three sources are presented: reports from six policlinics of dermatovenereology since 1973, laboratory reports of Neisseria gonorrhoeae, Treponema pallidum and Chlamydia trachomatis since 1988, and reports by the Swiss Sentinel Network between June 1991 and December 1993. The data indicate that there has been a decline in the number of cases of syphilis and, in particular, gonorrhoea since the early 1980s in Switzerland. Since many factors could explain the declines (e.g. more effective treatments, more widespread use of antibiotics, marked changes in behaviour such as increased levels of condom use) it is difficult to identify their exact causes. Evidence for two of the before-mentioned factors exists and these probably played important roles in the declines. Firstly, as a result of the emergence of penicillinase producing strains of N. gonorrhoeae, the introduction of new treatments for gonorrhoea in the early 1980s which were simpler to administer and more effective (in particular the use of spectinomycin). Secondly, the national AIDS prevention campaign which began in 1987 and has been associated with major increases in condom use in the Swiss population.

摘要

艾滋病毒/艾滋病的流行使得瑞士对性传播疾病(STD)的流行病学越来越关注。本文呈现了来自三个来源的性传播疾病监测数据:自1973年以来六家皮肤性病门诊的报告、自1988年以来淋病奈瑟菌、梅毒螺旋体和沙眼衣原体的实验室报告,以及1991年6月至1993年12月期间瑞士哨点网络的报告。数据表明,自20世纪80年代初以来,瑞士梅毒病例数有所下降,尤其是淋病病例数。由于许多因素可以解释这种下降(例如更有效的治疗方法、抗生素的更广泛使用、行为的显著变化,如避孕套使用水平的提高),因此很难确定其确切原因。上述两个因素的证据是存在的,它们可能在这种下降中发挥了重要作用。首先,由于产生青霉素酶的淋病奈瑟菌菌株的出现,20世纪80年代初引入了更易于给药且更有效的淋病新治疗方法(特别是使用壮观霉素)。其次,始于1987年的全国艾滋病预防运动与瑞士人群中避孕套使用的大幅增加有关。

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