Milgram J W
J Bone Joint Surg Am. 1977 Sep;59(6):792-801.
In thirty cases of synovial osteochondromatosis studied clinically and pathologically, the process appeared to follow a temporal sequence characterized by three recognizable phases (1) active intrasynovial disease only, with no loose bodies; (2) transitional lesions with both active intrasynovial proliferation and free loose bodies; and (3) multiple free osteochondral bodies with no demonstrable intrasynovial disease. If gross examination at the time of surgery shows that the disease is in the third phase, it would appear that synovectomy may not be necessary. However, extrasynovial intra-articular cartilaginous lesions may persist after synovectomy in the other two phases and may grow, causing recurrence of clinical symptoms in the absence of new intrasynovial disease.
对30例经临床和病理研究的滑膜骨软骨瘤病病例而言，该病程似乎遵循一个具有三个可识别阶段的时间顺序：（1）仅为滑膜内活动性病变，无游离体；（2）过渡性病变，同时存在滑膜内活动性增生和游离的游离体；（3）多个游离的骨软骨体，无明显的滑膜内病变。如果手术时的大体检查显示疾病处于第三阶段，那么似乎滑膜切除术可能没有必要。然而，在其他两个阶段进行滑膜切除术后，滑膜外关节内软骨病变可能持续存在并可能生长，在无新的滑膜内病变的情况下导致临床症状复发。
