Belli L, Magistretti G, Puricelli G P, Damiani G, Colombo E, Cornalba G P
Department of Radiology, Ospedale Multizonale, Viale Borri 57, I-21100 Varese, Italy.
Eur Radiol. 1997;7(3):323-6. doi: 10.1007/s003300050159.
Primary and metastatic tumors of the liver can be treated successfully with transcatheter chemoembolization (TACE) during selective arterial catheterism. Arteritis is a possible referred side effect which can lead to tortuosity of the arteries, stenosis and occlusion of vessels. In our hospitals 117 consecutive patients were treated with TACE from January 1990 to December 1992; 61 patients were affected by hepatocellular carcinoma (HCC) and 56 were affected by metastases from colorectal carcinoma. Each patient received from 1 to 4 treatments at monthly intervals using epirubicin/Lipiodol ultrafluid (E/LUF) or a mixture of epirubicin and mitomicin C (MC)/LUF and followed by gelatine sponge injection in the hepatic artery. Selective angiography performed 30-62 days after the first chemoembolization showed artery stenosis in 7 patients and thrombosis in 2 cases related to toxic arteritis due to chemoembolization. Reports about arteritis during TACE treatments are discussed.
在选择性动脉插管期间，原发性和转移性肝癌均可通过经导管化疗栓塞术（TACE）成功治疗。动脉炎是一种可能出现的副作用，可导致动脉迂曲、血管狭窄和闭塞。1990年1月至1992年12月，我院连续117例患者接受了TACE治疗；其中61例为肝细胞癌（HCC）患者，56例为结直肠癌转移患者。每位患者每月接受1至4次治疗，使用表柔比星/超液化碘油（E/LUF）或表柔比星与丝裂霉素C（MC）的混合物/LUF，随后在肝动脉内注射明胶海绵。首次化疗栓塞后30 - 62天进行的选择性血管造影显示，7例患者出现动脉狭窄，2例出现与化疗栓塞所致毒性动脉炎相关的血栓形成。文中讨论了有关TACE治疗期间动脉炎的报告。
