Gürsel T, Firat S, Ercan Z S
Department of Pediatric Hematology, Faculty of Medicine, Gazi University, Ankara, Turkey.
Prostaglandins Leukot Essent Fatty Acids. 1997 Mar;56(3):205-7. doi: 10.1016/s0952-3278(97)90535-4.
The possible association of leukotriene B4 (LTB4)-like activity with the development of active rheumatoid arthritis was studied in 25 children with the disease and in 15 normal subjects. Serum LTB4-like activity was found to be significantly higher in the active stage of the disease when compared with the values obtained from patients during the inactive stage and from healthy children. No correlation was found between LTB4-activity and other laboratory parameters, e.g. haemoglobin level, white cell count and erythrocyte sedimentation rate.
在25例患有活动性类风湿关节炎的儿童和15名正常受试者中，研究了白三烯B4（LTB4）样活性与活动性类风湿关节炎发展之间的可能关联。与疾病非活动期患者及健康儿童所测得的值相比，发现疾病活动期的血清LTB4样活性显著更高。未发现LTB4活性与其他实验室参数之间存在相关性，例如血红蛋白水平、白细胞计数和红细胞沉降率。
