核苷酸酰胺的核磁共振。脱氧腺苷酰基-（5'-3'）-脱氧腺苷酰基-（5'至N）-L-苯丙氨酸甲酯二级结构的研究。
Nuclear magnetic resonance of nucleotide-amidates. Investigation of the secondary structure of methylester of deoxyadenylyl-(5'-3')-deoxyadenylyl-(5' leads to N)-L-phenylalanine.
作者信息
Tyaglov B V, Zenin S V
出版信息
Nucleic Acids Res. 1977 Aug;4(8):2609-17. doi: 10.1093/nar/4.8.2609.
Abstract
The secondary structure of methyl ester of deoxyadenylyl- - (5' - 3') - deoxyadenylyl - (5' leads to N) - L-phenylalanine / L- PheOMe - d(pApA)/ was investigated using proton magnetic resonance. The folded conformation stabilized by hydrophobic interactions in aqueous solution was shown for this compound. The investigation of the chemical shifts of aromatic protons of L- PheoOMe - d(pApA) permitted us to construct the conformational model of this compound.
摘要
使用质子磁共振研究了脱氧腺苷酰基 - （5' - 3'） - 脱氧腺苷酰基 - （5' 至 N） - L - 苯丙氨酸甲酯/L - PheOMe - d（pApA）的二级结构。该化合物在水溶液中通过疏水相互作用稳定的折叠构象得以展现。对L - PheoOMe - d（pApA）芳香族质子化学位移的研究使我们能够构建该化合物的构象模型。
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本文引用的文献
1
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J Am Chem Soc. 1969 Jan 1;91(1):168-83. doi: 10.1021/ja01029a033.
2
Metal ion binding to adenosine triphosphate. 3. A kinetic analysis.金属离子与三磷酸腺苷的结合。3. 动力学分析。
J Am Chem Soc. 1968 Dec 4;90(25):7110-8. doi: 10.1021/ja01027a041.
3
4
A proton magnetic resonance study of metal ion-adenine ring interactions in metal ion complexes with adenosine triphosphate.金属离子与三磷酸腺苷形成的金属离子配合物中金属离子 - 腺嘌呤环相互作用的质子磁共振研究。
Biochemistry. 1971 Mar 2;10(5):843-51. doi: 10.1021/bi00781a018.
5
Intermolecular nuclear shielding values for protons of purines and flavins.嘌呤和黄素中质子的分子间核屏蔽值。
J Theor Biol. 1970 Apr;27(1):87-95. doi: 10.1016/0022-5193(70)90130-x.
6
Nuclear magnetic resonance studies of the structure and binding sites of enzymes. 8. Inhibitor binding to ribonuclease.酶的结构与结合位点的核磁共振研究。8. 抑制剂与核糖核酸酶的结合
J Mol Biol. 1969 Nov 14;45(3):491-511. doi: 10.1016/0022-2836(69)90308-8.
7
Fluorescence studies of the interaction of nucleotides with the active site of the nuclease of Staphylococcus aureus.核苷酸与金黄色葡萄球菌核酸酶活性位点相互作用的荧光研究。
Proc Natl Acad Sci U S A. 1967 Nov;58(5):2043-50. doi: 10.1073/pnas.58.5.2043.
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