螺旋喹诺霉素，一种由链霉菌属MJ929-SF2 II产生的新型DNA解旋酶抑制剂。螺旋喹诺霉素的结构测定。
Heliquinomycin, a new inhibitor of DNA helicase, produced by Streptomyces sp. MJ929-SF2 II. Structure determination of heliquinomycin.
作者信息
Chino M, Nishikawa K, Tsuchida T, Sawa R, Nakamura H, Nakamura K T, Muraoka Y, Ikeda D, Naganawa H, Sawa T, Takeuchi T
机构信息
Institute of Microbial Chemistry, Tokyo, Japan.
出版信息
J Antibiot (Tokyo). 1997 Feb;50(2):143-6. doi: 10.7164/antibiotics.50.143.
PMID:9099224
Abstract
The structure of heliquinomycin which was isolated from the culture broth of Streptomyces sp. MJ929-SF2 was studied by NMR spectroscopies, X-ray crystallographic analysis and degradation experiments. Heliquinomycin is the first member of glycosylated rubromycins and griseorhodins group antibiotics.
摘要
对从链霉菌属MJ929 - SF2的培养液中分离出的日光霉素的结构进行了核磁共振光谱分析、X射线晶体学分析和降解实验研究。日光霉素是糖基化红菌素和灰红菌素类抗生素中的首个成员。
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