Robin L F, Beller M, Middaugh J P
Epidemic Intelligence Service, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
Pediatrics. 1997 Apr;99(4):E9. doi: 10.1542/peds.99.4.e9.
Lead poisoning is a well-recognized public health concern for children living in the United States. In 1992, Health Care Financing Administration (HCFA) regulations required lead poisoning risk assessment and blood lead testing for all Medicaid-enrolled children ages 6 months to 6 years. This study estimated the prevalence of blood lead levels (BLLs) >/=10 microg/dL (>/=0.48 micromol/L) and the performance of risk assessment questions among children receiving Medicaid services in Alaska.
Measurement of venous BLLs in a statewide sample of children and risk assessment using a questionnaire modified from HCFA sample questions.
Eight urban areas and 25 rural villages throughout Alaska.
Nine hundred sixty-seven children enrolled in Medicaid, representing a 6% sample of 6-month- to 6-year-old Alaska children enrolled in Medicaid.
OUTCOME MEASURE(S): Determination of BLL and responses to verbal-risk assessment questions.
BLLs ranged from <1 microg/dL (<0.048 micromol/L) to 21 microg/dL (1.01 micromol/L) (median, 2.0 microg/dL or 0.096 micromol/L). The geometric mean BLLs for rural and urban children were 2.2 microg/dL (0.106 micromol/L) and 1.5 microg/dL (0.072 micromol/L), respectively. Six (0.6%) children had a BLL >/=10 microg/dL; only one child had a BLL >/=10 microg/dL (11 microg/dL or 0.53 micromol/L) on retesting. Children whose parents responded positively to at least one risk factor question were more likely to have a BLL >/=10 microg/dL (prevalence ratio = 3.1; 95% confidence interval = 0.4 to 26.6); the predictive value of a positive response was <1%.
In this population, the prevalence of lead exposure was very low (0.6%); only one child tested (0.1%) maintained a BLL >/=10 microg/dL on confirmatory testing; no children were identified who needed individual medical or environmental management for lead exposure. Universal lead screening for Medicaid-enrolled children is not an effective use of public health resources in Alaska. Our findings identify an example of the importance in considering local and regional differences when formulating screening recommendations and regulations, and continually reevaluating the usefulness of federal regulations.
铅中毒是美国儿童中一个公认的公共卫生问题。1992年,医疗保健财务管理局(HCFA)规定,所有参加医疗补助计划的6个月至6岁儿童都要进行铅中毒风险评估和血铅检测。本研究估计了阿拉斯加接受医疗补助服务儿童的血铅水平(BLLs)≥10微克/分升(≥0.48微摩尔/升)的患病率以及风险评估问题的有效性。
对全州范围内的儿童样本进行静脉血铅水平测量,并使用根据HCFA样本问题修改的问卷进行风险评估。
阿拉斯加的8个城市地区和25个乡村。
967名参加医疗补助计划的儿童,占阿拉斯加参加医疗补助计划的6个月至6岁儿童的6%。
测定血铅水平以及对口头风险评估问题的回答。
血铅水平范围为<1微克/分升(<0.048微摩尔/升)至21微克/分升(1.01微摩尔/升)(中位数为2.0微克/分升或0.096微摩尔/升)。农村和城市儿童的几何平均血铅水平分别为2.2微克/分升(0.106微摩尔/升)和1.5微克/分升(0.072微摩尔/升)。6名(0.6%)儿童的血铅水平≥10微克/分升;再次检测时只有1名儿童的血铅水平≥10微克/分升(11微克/分升或0.53微摩尔/升)。父母对至少一个风险因素问题回答为阳性的儿童,其血铅水平≥10微克/分升的可能性更大(患病率比=3.1;95%置信区间=0.4至26.6);阳性回答的预测价值<1%。
在这个群体中,铅暴露的患病率非常低(至0.6%);只有一名接受检测的儿童(0.1%)在确认检测时血铅水平≥10微克/分升;没有发现需要针对铅暴露进行个体医疗或环境管理的儿童。对参加医疗补助计划的儿童进行普遍铅筛查在阿拉斯加并非有效利用公共卫生资源的方式。我们的研究结果表明,在制定筛查建议和规定时考虑当地和地区差异以及不断重新评估联邦规定的有用性非常重要。