Eiraldi R B, Power T J, Nezu C M
University of Pennsylvania School of Medicine, Philadelphia 19104, USA.
J Am Acad Child Adolesc Psychiatry. 1997 Apr;36(4):503-14. doi: 10.1097/00004583-199704000-00013.
To study externalizing and internalizing comorbidity patterns in 6- to 12-year-old children with attention-deficit/hyperactivity disorder (ADHD) combined subtype (n = 27), ADHD inattentive subtype (n = 26), and a normal control group (n = 33).
Children were assigned to groups on the basis of results of a parent structured interview, which reflected DSM-IV diagnostic criteria, and teacher ratings of ADHD symptoms. Comorbid problems were assessed via parent and child structured interviews and parent and teacher behavior ratings.
Logistic regression analyses and multivariate analyses of covariance revealed that (1) children in the ADHD combined group were significantly more likely to have a diagnosis of oppositional defiant disorder and conduct disorder and had significantly higher scores on parent and teacher ratings of externalizing problems than children in the ADHD inattentive and control groups, (2) children in the ADHD combined and ADHD inattentive groups had significantly higher scores on parent and teacher ratings of internalizing problems than children in the control group, and (3) children in the clinical groups did not differ with regard to internalizing disorders.
The results from this study indicate that a significant comorbidity exists between ADHD combined and oppositional defiant disorder/conduct disorder. Contrary to previous studies that were conducted using DSM-III diagnostic criteria for ADHD, no differences were found between ADHD combined and ADHD inattentive subtypes regarding internalizing disorders.
研究6至12岁注意力缺陷多动障碍(ADHD)混合型(n = 27)、ADHD注意力不集中型(n = 26)儿童以及正常对照组(n = 33)的外化性和内化性共病模式。
根据反映《精神疾病诊断与统计手册》第四版(DSM-IV)诊断标准的家长结构化访谈结果以及教师对ADHD症状的评分,将儿童分组。通过家长和儿童结构化访谈以及家长和教师行为评分来评估共病问题。
逻辑回归分析和多变量协方差分析显示:(1)与ADHD注意力不集中组和对照组儿童相比,ADHD混合型组儿童被诊断为对立违抗障碍和品行障碍的可能性显著更高,且在外化性问题的家长和教师评分上得分显著更高;(2)与对照组儿童相比,ADHD混合型组和ADHD注意力不集中组儿童在内化性问题的家长和教师评分上得分显著更高;(3)临床组儿童在内化性障碍方面没有差异。
本研究结果表明,ADHD混合型与对立违抗障碍/品行障碍之间存在显著共病。与以往使用DSM-III诊断标准进行的ADHD研究相反,ADHD混合型和ADHD注意力不集中型在内化性障碍方面未发现差异。