Lu C P, Chang T C, Wang C Y, Hsiao Y L
Department of Internal Medicine, National Taiwan University Hospital, Taipei, Republic of China.
Acta Cytol. 1997 Mar-Apr;41(2):238-43. doi: 10.1159/000332449.
To elucidate the serial cytologic presentations of subacute thyroiditis (SAT) with ultrasound-guided fine needle aspiration (FNA).
Nine patients with clinically evident SAT were recruited; serial sonography and ultrasound-guided fine needle aspiration cytology were performed.
Sixty-one follow-up examinations were obtained in nine patients. The follow-up ranged from 1 to 5 months (mean, 3.3). Initial sonographic presentations revealed focal hypoechogenicity in three patients and multiple hypoechogenicity in six. Initial cytologic findings showed chiefly enlarged, degenerated follicular cells with prominent nucleoli, lymphocytes, colloid substance, multinucleated giant cells and neutrophils. Regression of sonographic hypoechogenicity paralleled the disappearance of acute inflammatory cells and enlarged, degenerated follicular cells and the appearance of cohesive follicles.
Improvement of SAT in sonography is fairly parallel to that in cytology even though there is a lag of improvement in the latter. Smear pattern is also related to the clinical stage of SAT. Ultrasound-guided FNA is a convenient method of obtaining sufficient and representative specimens in patients with SAT.
通过超声引导下细针穿刺活检（FNA）阐明亚急性甲状腺炎（SAT）的系列细胞学表现。
招募9例临床确诊为SAT的患者；进行系列超声检查及超声引导下细针穿刺细胞学检查。
9例患者共进行了61次随访检查。随访时间为1至5个月（平均3.3个月）。最初的超声表现显示，3例患者为局灶性低回声，6例为多发低回声。最初的细胞学检查结果主要显示为增大、变性的滤泡细胞，伴有明显核仁、淋巴细胞、胶质物质、多核巨细胞和中性粒细胞。超声低回声的消退与急性炎症细胞、增大和变性的滤泡细胞的消失以及紧密滤泡的出现平行。
尽管SAT的细胞学改善存在滞后，但超声表现的改善与细胞学改善相当平行。涂片模式也与SAT的临床分期有关。超声引导下FNA是一种为SAT患者获取足够且有代表性标本的便捷方法。
