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胃肠内镜检查中的抗生素预防:英国胃肠病学会内镜委员会工作小组的报告

Antibiotic prophylaxis in gastrointestinal endoscopy: a report by a Working Party for the British Society of Gastroenterology Endoscopy Committee.

作者信息

Mani V, Cartwright K, Dooley J, Swarbrick E, Fairclough P, Oakley C

机构信息

Dept. of Gastroenterology, Leigh Infirmary, Lancashire, United Kingdom.

出版信息

Endoscopy. 1997 Feb;29(2):114-9. doi: 10.1055/s-2007-1004085.

Abstract

Antibiotic prophylaxis is recommended for endoscopic procedures if the patient is at high risk of endocarditis or of symptomatic bacteraemia as a consequence of immunosuppression or neutropenia. In most circumstances parenteral amoxycillin and gentamicin are recommended. The addition of parenteral metronidazole is recommended in patients with neutropenia. Vancomycin or teicoplanin are recommended in patients allergic to penicillin. Antibiotic prophylaxis is recommended for all patients undergoing ERCP with evidence of biliary stasis or pancreatic pseudocyst. Oral ciprofloxacin or parenteral gentamicin (or parenteral quinolone, cephalosporin or ureidopenicillin) are recommended for ERCP.

摘要

如果患者因免疫抑制或中性粒细胞减少而有发生心内膜炎或有症状菌血症的高风险,则建议在内镜检查时进行抗生素预防。在大多数情况下,推荐使用静脉注射阿莫西林和庆大霉素。对于中性粒细胞减少的患者,建议加用静脉注射甲硝唑。对青霉素过敏的患者,推荐使用万古霉素或替考拉宁。对于所有接受内镜逆行胰胆管造影(ERCP)且有胆汁淤积或胰腺假性囊肿证据的患者,建议进行抗生素预防。对于ERCP,推荐口服环丙沙星或静脉注射庆大霉素(或静脉注射喹诺酮类、头孢菌素类或脲基青霉素)。

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