• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

低位直肠癌的保肛手术

[Sphincter saving procedure for low rectal carcinoma].

作者信息

Sugihara K, Moriya Y, Akasu T, Fujita S

机构信息

Department of Surgery, National Cancer Center Hospital, Tokyo, Japan.

出版信息

Nihon Geka Gakkai Zasshi. 1997 Mar;98(3):391-5.

PMID:9101547
Abstract

Sphincter saving procedure (SSP) was applied when, for tumor which were a localized type and well or moderate differentiated adenocarcinoma, distal clearance margin (AW) more than 2 cm was obtained and when, for tumor which was a infiltrated type or adenocarcinoma with other pathological grades, AW more than 3 cm was obtained. Between 1984 and 1993, 209 patients with rectal carcinomas, the lower border of which was located below the peritoneal reflexion, underwent curative surgery: SSP in 114 and abdominoperineal resection (APR) in 95. The APR group included more advanced cases both in the depth of invasion and in lymph node metastases (p = 0.011, p = 0.059, respectively). During the median follow-up of 68.6 months, recurrent tumors were developed in 17.5% of the SSP and in 30.5% of the APR (p = 0.027). The patients with SSP showed better prognosis than those with APR(p = 0.0007), with the 5 year survival rate of 80.2% and 70.0%, respectively. The difference may be due to higher incidence of hematogenous metastases in the APR (26.3%) than in the SSP (13.2%). There was no difference in local recurrences between them. When function after SSP was compared with that after anterior resection for middle or upper rectal carcinomas, no difference was observed between them, although most patients of the both groups complained of increased frequency of defecation and occasional soiling. The criteria of SSP for low located rectal carcinoma may be adequate with the acceptable oncological outcome, but altered function after SSP should be improved.

摘要

对于局限性、高分化或中分化腺癌的肿瘤,当远端切缘(AW)大于2 cm时,以及对于浸润型或其他病理分级的腺癌,当AW大于3 cm时,采用保括约肌手术(SSP)。1984年至1993年期间,209例下缘位于腹膜反折以下的直肠癌患者接受了根治性手术:114例行SSP,95例行腹会阴联合切除术(APR)。APR组在浸润深度和淋巴结转移方面均包括更晚期的病例(分别为p = 0.011,p = 0.059)。在中位随访68.6个月期间,SSP组17.5%出现复发性肿瘤,APR组为30.5%(p = 0.027)。SSP患者的预后优于APR患者(p = 0.0007),5年生存率分别为80.2%和70.0%。这种差异可能是由于APR组血行转移发生率(26.3%)高于SSP组(13.2%)。两组局部复发率无差异。将SSP后的功能与中高位直肠癌前切除术后的功能进行比较时,两组之间未观察到差异,尽管两组大多数患者都抱怨排便频率增加和偶尔失禁。低位直肠癌SSP的标准可能是合适的,肿瘤学结果可以接受,但SSP后改变的功能应得到改善。

相似文献

1
[Sphincter saving procedure for low rectal carcinoma].低位直肠癌的保肛手术
Nihon Geka Gakkai Zasshi. 1997 Mar;98(3):391-5.
2
Sphincter preservation in low rectal cancer is facilitated by preoperative chemoradiation and intersphincteric dissection.术前放化疗及括约肌间分离有助于低位直肠癌保肛。
Ann Surg. 2009 Feb;249(2):236-42. doi: 10.1097/SLA.0b013e318195e17c.
3
Multimedia article. Laparoscopic ultralow anterior resection with colonic J-pouch-anal anastomosis.多媒体文章。腹腔镜超低位前切除术联合结肠J形贮袋肛管吻合术。
Dis Colon Rectum. 2008 Nov;51(11):1710-1. doi: 10.1007/s10350-008-9322-4. Epub 2008 Aug 5.
4
Survival and recurrence after a sphincter-saving resection and abdominoperineal resection for adenocarcinoma of the rectum at or below the peritoneal reflection: a multivariate analysis.腹膜反折以下直肠癌行保留括约肌切除术和腹会阴联合切除术的生存及复发情况:多因素分析
Surg Today. 2004;34(1):32-9. doi: 10.1007/s00595-003-2637-9.
5
Magnetic resonance imaging predicts sphincter invasion of low rectal cancer and influences selection of operation.磁共振成像可预测低位直肠癌的括约肌侵犯情况并影响手术方式的选择。
Surgery. 2003 Jun;133(6):656-61. doi: 10.1067/msy.2003.150.
6
Anal sphincter preservation in locally advanced low rectal adenocarcinoma after preoperative chemoradiation therapy and coloanal anastomosis.术前放化疗及结肠肛管吻合术后局部进展期低位直肠癌的肛门括约肌保留
J Surg Oncol. 2003 Jan;82(1):3-9. doi: 10.1002/jso.10185.
7
Oncological outcomes after total mesorectal excision for cure for cancer of the lower rectum: anterior vs. abdominoperineal resection.低位直肠癌根治性全直肠系膜切除术后的肿瘤学结局:前切除术与腹会阴联合切除术的比较
Dis Colon Rectum. 2004 Jan;47(1):48-58. doi: 10.1007/s10350-003-0012-y. Epub 2004 Jan 14.
8
Long-term results using local excision after preoperative chemoradiation among selected T3 rectal cancer patients.部分T3期直肠癌患者术前放化疗后采用局部切除的长期结果。
Int J Radiat Oncol Biol Phys. 2004 Nov 15;60(4):1098-105. doi: 10.1016/j.ijrobp.2004.04.062.
9
Early results of intersphincteric resection for patients with very low rectal cancer: an active approach to avoid a permanent colostomy.极低位直肠癌患者行括约肌间切除术的早期结果:一种避免永久性结肠造口术的积极方法。
Dis Colon Rectum. 2004 Apr;47(4):459-66. doi: 10.1007/s10350-003-0088-4. Epub 2004 Feb 25.
10
Distal cT2N0 rectal cancer: is there an alternative to abdominoperineal resection?远端cT2N0期直肠癌:是否存在腹会阴联合切除术的替代方案?
J Clin Oncol. 2005 Aug 1;23(22):4905-12. doi: 10.1200/JCO.2005.10.041.