Ventura J E, Villa M, Mizraji R, Ferreiros R
Centro de Nefrología, Hospital de Clinicas, Universidad de la Republica, Montevideo, Uruguay.
Ren Fail. 1997 Mar;19(2):217-20. doi: 10.3109/08860229709026279.
From 1976 to 1994, 57 women were referred to the Centro de Nefrología, Montevideo, with obstetric acute renal failure (ARF). The main causes were hypertensive disorders such as preeclampsia (PE) in 27, acute pyelonephritis of pregnancy (APN) in 26, and idiopathic postpartum renal failure in 3. Severe preeclampsia superimposed on chronic hypertension and acute pyelonephritis of pregnancy complicated by sepsis accounted for more than 50% of the cases of ARF. Chronic renal failure developed in 6 patients: 2 had bilateral renal cortical necrosis, 1 had malignant nephrosclerosis, and 3 had idiopathic postpartum renal failure. Maternal mortality related to ARF was low in this group of patients (less than 2%). In contrast, perinatal mortality was strikingly high (40%).
1976年至1994年期间，57名患有产科急性肾衰竭（ARF）的女性被转诊至蒙得维的亚的肾病中心。主要病因包括高血压疾病，如27例先兆子痫（PE）、26例妊娠急性肾盂肾炎（APN）以及3例特发性产后肾衰竭。重度先兆子痫合并慢性高血压以及妊娠急性肾盂肾炎合并败血症占急性肾衰竭病例的50%以上。6例患者发展为慢性肾衰竭：2例为双侧肾皮质坏死，1例为恶性肾硬化，3例为特发性产后肾衰竭。该组患者中与急性肾衰竭相关的孕产妇死亡率较低（不到2%）。相比之下，围产期死亡率极高（40%）。
