与妊娠肾盂肾炎患者大肠杆菌的Dr操纵子相关的侵袭性
Dr operon-associated invasiveness of Escherichia coli from pregnant patients with pyelonephritis.
作者信息
Goluszko P, Niesel D, Nowicki B, Selvarangan R, Nowicki S, Hart A, Pawelczyk E, Das M, Urvil P, Hasan R
机构信息
Departments of Obstetrics and Gynecology, University of Texas Medical Branch, Galveston, Texas 77555, USA.
出版信息
Infect Immun. 2001 Jul;69(7):4678-80. doi: 10.1128/IAI.69.7.4678-4680.2001.
Abstract
We used a gentamicin protection assay to assess the ability of gestational pyelonephritis isolates of Escherichia coli to invade HeLa cells. The ability to enter HeLa cells was strongly associated with the presence of Dr operons coding for Dr adhesins. In contrast, the nonivasive isolates predominantly expressed papG, coding for P fimbriae.
摘要
我们采用庆大霉素保护试验来评估妊娠期肾盂肾炎大肠杆菌分离株侵袭HeLa细胞的能力。进入HeLa细胞的能力与编码Dr黏附素的Dr操纵子的存在密切相关。相比之下，非侵袭性分离株主要表达编码P菌毛的papG。
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