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全科医生开具苯二氮䓬类催眠药的处方模式:老年患者是否面临过量开药的特殊风险?来自默勒与罗斯达尔处方研究的报告。

General practitioners' prescribing patterns of benzodiazepine hypnotics: are elderly patients at particular risk for overprescribing? A report from the Møre & Romsdal Prescription Study.

作者信息

Straand J, Rokstad K

机构信息

Department of Public Health and Primary Health Care, University of Bergen, Norway.

出版信息

Scand J Prim Health Care. 1997 Mar;15(1):16-21. doi: 10.3109/02813439709043423.

Abstract

OBJECTIVE

To compare general practitioners' (GPs) prescribing patterns of benzodiazepine hypnotics with current recommendations.

DESIGN

Observational, cross-sectional study.

SETTING

The Norwegian county Møre and Romsdal.

SUBJECTS

3452 prescriptions for benzodiazepine hypnotics prescribed by GPs for patients aged 20 years and older during two months.

MAIN OUTCOME MEASURES

Prescriptions (strength of tablets, amount prescribed given in Defined and Prescribed Daily Doses: DDDs and PDDs, directions for use); initial or repeat, patients (age, sex); kind of GP-patient contact during prescribing.

RESULTS

68.4% of the prescriptions for benzodiazepine hypnotics were for women; 52.7% were for patients aged 65 or older (65+); 59.9% were issued during indirect contacts; 81.9% were repeat prescriptions. The amount of drug per prescription increased with patients' age: 65+ received on average 69.9 DDDs (76.9 PDDs) per prescription compared with 34.4 DDDs (37.1 PDDs) for young adults (20-29 years). About four of five prescriptions were for the "strong" (i.e. 1 tablet = 1 DDD) sleeping pills irrespective of patients' age and type of prescription (initial or repeat). Written directions for use were: "to be taken daily" in 55.1%, and "only if required" in 38.0% of the prescriptions. Written information on duration of "cure" was only found in one case.

CONCLUSIONS

GPs' prescribing patterns are not in accordance with recommended dosage and duration of treatment; this pattern is most pronounced for elderly patients.

摘要

目的

比较全科医生(GP)开具苯二氮䓬类催眠药的处方模式与当前建议。

设计

观察性横断面研究。

地点

挪威默勒-鲁姆斯达尔郡。

研究对象

全科医生在两个月内为20岁及以上患者开具的3452张苯二氮䓬类催眠药处方。

主要观察指标

处方(药片强度、以限定日剂量和规定日剂量给出的处方量:DDD和PDD、使用说明);初次或重复处方、患者(年龄、性别);开处方时全科医生与患者的接触类型。

结果

68.4%的苯二氮䓬类催眠药处方是开给女性的;52.7%是开给65岁及以上(65+)患者的;59.9%是在间接接触时开具的;81.9%是重复处方。每张处方的药物量随患者年龄增加:65岁及以上患者每张处方平均接受69.9 DDD(76.9 PDD),而年轻人(20 - 29岁)为34.4 DDD(37.1 PDD)。约五分之四的处方是开“强效”(即1片 = 1 DDD)安眠药,无论患者年龄和处方类型(初次或重复)。书面使用说明为:55.1%的处方是“每日服用”,38.0%是“仅在需要时服用”。仅在一例中发现了关于“疗程”的书面信息。

结论

全科医生的处方模式不符合推荐的剂量和治疗疗程;这种模式在老年患者中最为明显。

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