Fass J, Hungs M, Reinecke T, Schumpelick V
Chirurgische Universitätsklinik, RWTH Aachen.
Langenbecks Arch Chir Suppl Kongressbd. 1996;113:176-8.
The influence of D2-lymphadenectomy on staging and prognosis of gastric cancer was evaluated in a study including 195 consecutive patients (1986-1994). An impressive state migration could be proven in the UICC stages II, IIIa und IIIb, which led to significant differences in the survival rates for stages II and IIIa. We conclude that an extended lymphadenectomy contributes mainly to the accuracy of staging, while the improvement of the survival rates in studies comparing D1- with D2-lymphadenectomy is caused mainly by stage migration ("Will-Rogers phenomenon").
在一项纳入195例连续患者(1986 - 1994年)的研究中,评估了D2淋巴结清扫术对胃癌分期及预后的影响。在国际抗癌联盟(UICC)II期、IIIa期和IIIb期可证实存在显著的分期迁移,这导致II期和IIIa期的生存率存在显著差异。我们得出结论,扩大淋巴结清扫术主要有助于提高分期的准确性,而在比较D1和D2淋巴结清扫术的研究中生存率的提高主要是由分期迁移(“威尔 - 罗杰斯现象”)所致。