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[70岁以上老年患者胰腺癌的外科治疗]

[Surgical therapy of pancreatic carcinoma in elderly patients over 70].

作者信息

Richter A, Schwab M, Lorenz D, Rumstadt B, Trede M

机构信息

Chirurgische Klinik, Klinikum Mannheim, Klinische Fakultät, Universität Heidelberg.

出版信息

Langenbecks Arch Chir Suppl Kongressbd. 1996;113:492-4.

PMID:9101910
Abstract

Between October 1972 and December 1994, 519 pancreatic resections were performed at the Chirurgische Universitätsklinik Mannheim, 372 for pancreatic carcinoma. Of 328 patients who underwent a partial duodenopancreatectomy for cancer, 45 patients were older than 70 years: only in one case a partial duodenopancreatectomy was performed for chronic pancreatitis. In comparison to all patients the perioperative morbidity increased to 39.1% (21.5% vs. 39.1%). The perioperative mortality of all patients was 1.9%, the mortality of patients older than 70 years was 4.3%. The mean survival time of 28 patients who died subsequently was 30.6 (5-96) months. Despite increased perioperative morbidity and mortality, the patient's age is not considered to be a limiting factor to an attempt at curative resection of pancreatic or periampullary cancer.

摘要

1972年10月至1994年12月期间,曼海姆大学外科诊所共进行了519例胰腺切除术,其中372例为胰腺癌手术。在328例因癌症接受部分十二指肠胰腺切除术的患者中,45例年龄超过70岁:仅1例因慢性胰腺炎进行了部分十二指肠胰腺切除术。与所有患者相比,围手术期发病率增至39.1%(21.5%对39.1%)。所有患者的围手术期死亡率为1.9%,70岁以上患者的死亡率为4.3%。随后死亡的28例患者的平均生存时间为30.6(5 - 96)个月。尽管围手术期发病率和死亡率有所增加,但患者年龄不应被视为胰腺癌或壶腹周围癌根治性切除尝试的限制因素。

相似文献

1
[Surgical therapy of pancreatic carcinoma in elderly patients over 70].[70岁以上老年患者胰腺癌的外科治疗]
Langenbecks Arch Chir Suppl Kongressbd. 1996;113:492-4.
2
[Surgical therapy of pancreatic and periampullary carcinoma in elderly patients].老年患者胰腺和壶腹周围癌的外科治疗
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引用本文的文献

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Pancreatic resection in elderly patients: should it be denied?老年患者的胰腺切除术:是否应被拒绝?
Langenbecks Arch Surg. 2014 Apr;399(4):449-59. doi: 10.1007/s00423-014-1183-9. Epub 2014 Mar 27.
2
Pancreatic resection in the octogenarian: a safe option for pancreatic malignancy.80 岁以上人群的胰腺切除术:胰腺恶性肿瘤的安全选择。
J Am Coll Surg. 2011 Mar;212(3):373-7. doi: 10.1016/j.jamcollsurg.2010.10.015. Epub 2011 Jan 12.
3
What is the effect of age on pancreatic resection?年龄对胰腺切除术有何影响?
Adv Surg. 2009;43:233-49. doi: 10.1016/j.yasu.2009.02.004.
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The effect of age on short-term outcomes after pancreatic resection: a population-based study.年龄对胰腺切除术后短期结局的影响:一项基于人群的研究。
Ann Surg. 2008 Sep;248(3):459-67. doi: 10.1097/SLA.0b013e318185e1b3.