Richter A, Schwab M, Lorenz D, Rumstadt B, Trede M
Chirurgische Klinik, Klinikum Mannheim, Klinische Fakultät, Universität Heidelberg.
Langenbecks Arch Chir Suppl Kongressbd. 1996;113:492-4.
Between October 1972 and December 1994, 519 pancreatic resections were performed at the Chirurgische Universitätsklinik Mannheim, 372 for pancreatic carcinoma. Of 328 patients who underwent a partial duodenopancreatectomy for cancer, 45 patients were older than 70 years: only in one case a partial duodenopancreatectomy was performed for chronic pancreatitis. In comparison to all patients the perioperative morbidity increased to 39.1% (21.5% vs. 39.1%). The perioperative mortality of all patients was 1.9%, the mortality of patients older than 70 years was 4.3%. The mean survival time of 28 patients who died subsequently was 30.6 (5-96) months. Despite increased perioperative morbidity and mortality, the patient's age is not considered to be a limiting factor to an attempt at curative resection of pancreatic or periampullary cancer.
1972年10月至1994年12月期间,曼海姆大学外科诊所共进行了519例胰腺切除术,其中372例为胰腺癌手术。在328例因癌症接受部分十二指肠胰腺切除术的患者中,45例年龄超过70岁:仅1例因慢性胰腺炎进行了部分十二指肠胰腺切除术。与所有患者相比,围手术期发病率增至39.1%(21.5%对39.1%)。所有患者的围手术期死亡率为1.9%,70岁以上患者的死亡率为4.3%。随后死亡的28例患者的平均生存时间为30.6(5 - 96)个月。尽管围手术期发病率和死亡率有所增加,但患者年龄不应被视为胰腺癌或壶腹周围癌根治性切除尝试的限制因素。