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[老年患者的肝移植:适应证、风险与结果]

[Liver transplantation in elderly patients: indications, risks and results].

作者信息

Schlitt H J, Obed A, Oldhafer K J, Manns M P, Pichlmayr R

机构信息

Klinik für Abdominal- und Transplantationschirurgie, Medizinische Hochschule Hannover.

出版信息

Langenbecks Arch Chir Suppl Kongressbd. 1996;113:519-21.

PMID:9101918
Abstract

This study analyzes the course of 62 patients aged over 60 years (i.e., 7% of all recipients) which were liver transplanted over the last 10 years. The data show that the results of transplantation in patients with malignant tumors (n = 25) are unfavorable (20% 5-year survival), while good results could be obtained in patients with benign indications (n = 37), including mainly posthepatitic cirrhosis, but also three fulminant liver failures (75% 5-year survival). Causes of death were mainly septic complications in the early phase and tumor recurrence in patients with malignant disease.

摘要

本研究分析了过去10年中接受肝脏移植的62例60岁以上患者(即所有受者的7%)的病程。数据显示,患有恶性肿瘤的患者(n = 25)移植结果不佳(5年生存率为20%),而具有良性指征的患者(n = 37)可获得良好结果,主要包括肝炎后肝硬化患者,还有3例暴发性肝衰竭患者(5年生存率为75%)。死亡原因主要是早期的败血症并发症以及恶性疾病患者的肿瘤复发。

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