Siewert J R
Chirurgische Klinik und Poliklinik, Technische Universität München.
Langenbecks Arch Chir Suppl Kongressbd. 1996;113:56-63.
Radicality is the decisive aim in oncologic surgery. From a surgical point of view radicality provides the only chance of healing for the patient. Radicality can be defined and objectified. That means absence of tumor in all 3 dimensions of the primary tumor, that is the tumor bed as well. In the area of lymphatic drainage a most favourable lymph node ratio has to be achieved. At least the borderline lymph nodes must be free of tumor. However, an improvement of prognosis can only be achieved if the lymph node ratio is below 0.2. If the aim of a so-defined radicality cannot be safely achieved in a case of an advanced tumor stage, preoperative multimodal therapy can be tried. In responders, the aim of radicality can still be reached by these means. Postoperatively radicality is objectified by the pathologist. His findings are the objective basis for every further therapeutic consideration.
根治性是肿瘤外科手术的决定性目标。从外科手术的角度来看,根治性为患者提供了唯一的治愈机会。根治性可以被定义并客观化。这意味着在原发肿瘤的所有三个维度上都没有肿瘤,肿瘤床也是如此。在淋巴引流区域,必须实现最有利的淋巴结比例。至少边缘淋巴结必须无肿瘤。然而,只有当淋巴结比例低于0.2时,才能实现预后的改善。如果在晚期肿瘤病例中无法安全实现如此定义的根治性目标,可以尝试术前多模式治疗。对于有反应者,仍可通过这些方法实现根治性目标。术后根治性由病理学家客观判定。他的发现是进一步治疗考虑的客观依据。