Grübel P, Cave D R
Division of Gastroenterology, St. Elizabeth's Medical Center of Boston, USA.
Fortschr Med. 1997 Jan 30;115(3):35-6.
The route by which humans get infected with H.p. is unknown. Viable bacteria have been shown to be excreted in human feces from infected individuals. We have recently shown that flies are able to carry and disseminate viable H. p. with their excreta, when they have fed on H.p. We propose a hypothesis that H. p. is acquired from human feces by flies, which then, while crawling on human food, contaminate it with their intestinal excreta. The food, swallowed by a susceptible individual then leads to a new infection. Flies should be considered prime suspects for the transmission of H. p., particularly in developing countries, where sanitary and domestic facilities are poor.
人类感染幽门螺杆菌(H.p.)的途径尚不清楚。已证明有活力的细菌可从受感染个体的粪便中排出。我们最近发现,苍蝇在食用幽门螺杆菌后,能够通过排泄物携带并传播有活力的幽门螺杆菌。我们提出一个假说,即苍蝇从人类粪便中获取幽门螺杆菌,然后在人类食物上爬行时,用其肠道排泄物污染食物。易感个体吞咽这些食物后会导致新的感染。苍蝇应被视为幽门螺杆菌传播的主要嫌疑对象,尤其是在卫生和家庭设施较差的发展中国家。