肾移植受者接受环孢素治疗后的卡氏肺孢子虫肺炎
[Pneumocystis carinii pneumonia in renal transplant recipients treated with cyclosporin].
作者信息
Kim C J, Pak K, Wakabayashi Y, Ishida A, Arai Y, Konishi T, Kounami T, Tomoyoshi T, Sako H, Okino K
机构信息
Group of Renal Transplantation, Shiga University of Medical Science.
出版信息
Hinyokika Kiyo. 1989 Apr;35(4):653-9.
Four cases of pneumocystis carinii pneumonia occurred among 38 renal transplant recipients. Diagnosis was confirmed by cyst concentration technique in 2 cases. The other 2 cases were clinically, from the rapid improvement of fever, pulmonary infiltrates and hypoxia following a therapeutic trial of high dose sulfamethoxazole-trimethoprim. All patients responded to treatment with high dose sulfamethoxazole-trimethoprim. Three patients survived pneumocystis carinii pneumonia, but i died due to aspergillosis. One patients showed serological evidence of concomitant cytomegalovirus infection.
38例肾移植受者中发生了4例卡氏肺孢子虫肺炎。2例通过囊肿浓缩技术确诊。另外2例根据临床症状，在大剂量磺胺甲恶唑-甲氧苄啶治疗试验后发热、肺部浸润和缺氧迅速改善而确诊。所有患者对大剂量磺胺甲恶唑-甲氧苄啶治疗均有反应。3例卡氏肺孢子虫肺炎患者存活，但1例死于曲霉病。1例患者有巨细胞病毒合并感染的血清学证据。
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