Vavić N, Vavić N, Slavković B, Pajević M, Djokić M
Department of Transfusiology and Immunohematology, Zvezdara University Medical Centre, Belgrade.
Srp Arh Celok Lek. 1996;124 Suppl 1:133-5.
Red cells depleted of white cells can prevent febrile nonhemolytic transfusion reactions and may reduce or delay alloimmunization of HLA antigens and the transfusion of various viruses. Twenty-three patients maintained on hemodialysis who had febrile nonhemolytic transfusion reactions were analysed between 1976 and 1994. This reaction was first noticed in patients diagnosed with chronic glomerulonephritis approximately after receiving 7.5 transfusions. The patients were treated with washed red cells from 1976 to 1988 and from this period to 1994 tewy were treated with filtered red cells via Sepacell R500-A. With the use of these preparations, the febrile nonhemolytic reaction was eliminated. The latest advances in transfusiology include the preparation of all blood components without leukocytes.
去除白细胞的红细胞可预防发热性非溶血性输血反应，并可能减少或延迟HLA抗原的同种免疫以及各种病毒的传播。对1976年至1994年间维持血液透析且发生发热性非溶血性输血反应的23例患者进行了分析。这种反应最早在诊断为慢性肾小球肾炎的患者中被注意到，大约在接受7.5次输血后出现。1976年至1988年期间，这些患者接受洗涤红细胞治疗，从这段时期到1994年，他们通过Sepacell R500-A接受过滤红细胞治疗。使用这些制剂后，发热性非溶血性反应得以消除。输血学的最新进展包括制备不含白细胞的所有血液成分。
