Kimura M, Furuta T, Hiruma S, Otsuka K, Teramura K, Maekura S, Satou T, Hashimoto S
Second Department of Pathology, Kinki University School of Medicine, Osaka-Sayama, Japan.
Pathol Int. 1997 Apr;47(4):256-9. doi: 10.1111/j.1440-1827.1997.tb04488.x.
Nemaline bodies were found in the regenerating muscle fibers of the neck of a 74-year-old Japanese male with pharyngeal cancer. Histologically, the nemaline bodies were needle-shaped structures and hematoxophilic with phosphotungstic acid-hematoxylin stain. Electron microscopic examination suggested that they arise as extensions of the Z bands. Although nemaline bodies occur in a variety of pathological conditions other than nemaline myopathy, their occurrence in regenerating skeletal muscle fibers invaded by cancer has not been reported previously. The pathogenesis of the nemaline body formation in the present case is discussed.
在一名患有咽癌的74岁日本男性颈部再生肌纤维中发现了杆状体。组织学上，杆状体为针状结构，磷钨酸苏木精染色呈嗜苏木精性。电子显微镜检查表明，它们是Z带的延伸。尽管杆状体可见于除杆状体肌病以外的多种病理状况，但此前尚未有其在受癌症侵袭的再生骨骼肌纤维中出现的报道。本文讨论了该病例中杆状体形成的发病机制。
