Keene W E, Sazie E, Kok J, Rice D H, Hancock D D, Balan V K, Zhao T, Doyle M P
Acute and Communicable Disease Program, Oregon Health Division, Portland 97232, USA.
JAMA. 1997 Apr 16;277(15):1229-31. doi: 10.1001/jama.1997.03540390059036.
To investigate a 1995 outbreak of Escherichia coli O157:H7 infections and to assess the safety of meat dehydration methods.
Survey subsequent to routine surveillance report, environmental investigations, and laboratory experimentation.
Oregon community.
Members of an extended household and their social contacts with confirmed or presumptive E coli O157:H7 infections.
A total of 6 confirmed and 5 presumptive cases were identified. Homemade venison jerky was implicated as the source of transmission. E coli O157:H7 with the same distinctive, pulsed-field gel electrophoresis pattern seen in the case isolates was recovered from leftover jerky, uncooked meat from the same deer, a saw used to dismember the carcass, and fragments of the deer hide. In a subsequent survey, E coli O157:H7 was recovered from 3 (9%) of 32 deer fecal pellets collected in nearby forest land. In the laboratory, inoculated venison was dried at several time and temperature combinations, ranging up to 10 hours at 62.8 degrees C. Viable organisms were recovered under all conditions tested.
Deer can be colonized by E coli O157:H7 and can be a source of human infections. Conditions necessary to ensure the safety of dried meat deserve further review. Game should be handled with the same caution indicated for commercially slaughtered meat.
调查1995年大肠杆菌O157:H7感染的暴发情况，并评估肉类脱水方法的安全性。
在常规监测报告、环境调查和实验室实验之后进行的调查。
俄勒冈州社区。
一个大家庭的成员及其与确诊或疑似大肠杆菌O157:H7感染的社会接触者。
共确定6例确诊病例和5例疑似病例。自制鹿肉干被认为是传播源。从剩余的肉干、同一头鹿的未煮过的肉、用于肢解鹿 carcass 的锯子以及鹿皮碎片中分离出了与病例分离株中所见相同独特脉冲场凝胶电泳图谱的大肠杆菌O157:H7。在随后的一项调查中，从附近林地采集的32份鹿粪便颗粒中的3份（9%）中分离出了大肠杆菌O157:H7。在实验室中，接种的鹿肉在几种时间和温度组合下进行干燥处理，最高温度为62.8摄氏度，干燥时间长达10小时。在所有测试条件下均能检测到存活的生物体。
鹿可被大肠杆菌O157:H7定植，并可能成为人类感染源。确保肉干安全性所需的条件值得进一步审查。处理野味时应与处理商业屠宰的肉类一样谨慎。
