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暴发的肠出血性大肠杆菌 O157 噬菌体 32 型与鹿肉产品消费有关。

Outbreak of Escherichia coli O157 Phage Type 32 linked to the consumption of venison products.

机构信息

Health Protection Scotland,Glasgow,Scotland.

Scottish E. coli O157/STEC Reference Laboratory,Edinburgh,Scotland.

出版信息

Epidemiol Infect. 2018 Nov;146(15):1922-1927. doi: 10.1017/S0950268818001784. Epub 2018 Jul 6.

Abstract

In September 2015, an outbreak of Escherichia coli Phage Type 32 with an indistinguishable multi locus variable number tandem repeat analysis profile was identified in Scotland. Twelve cases were identified; nine primary cases, two secondary and one asymptomatic case. Extensive food history investigations identified venison products containing wild venison produced by a single food business operator as the most likely source of the outbreak. Of the nine primary cases, eight had consumed venison products, and one case had not eaten venison themselves but had handled and cooked raw venison in the household. This was the first reported outbreak of Shiga toxin-producing Escherichia coli (STEC) linked to venison products in the UK, and was also notable due to the implicated products being commercially produced and widely distributed. In contrast, previous venison outbreaks reported from other countries have tended to be smaller and related to individually prepared carcases. The outbreak has highlighted some important knowledge gaps in relation to STEC in venison that are currently been investigated via a number of research studies.

摘要

2015 年 9 月,苏格兰发现了一种无法区分的多基因座可变数目串联重复分析谱的肠出血性大肠杆菌噬菌体 32 型。共发现了 12 例病例;9 例原发性病例,2 例继发性病例和 1 例无症状病例。广泛的食物史调查确定,含有单一食品加工商生产的野味鹿肉的鹿肉产品是此次暴发的最可能来源。在 9 例原发性病例中,有 8 例食用了鹿肉产品,1 例病例没有食用鹿肉,但在家庭中处理和烹饪了生鹿肉。这是在英国首次报告与鹿肉产品相关的产志贺毒素大肠杆菌(STEC)暴发,并且由于所涉及的产品是商业化生产和广泛分布的,因此值得注意。相比之下,其他国家以前报告的鹿肉暴发规模较小,且与个别准备的鹿肉有关。此次暴发突出了一些与鹿肉中 STEC 相关的重要知识空白,目前正在通过多项研究进行调查。

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