Begum F, Buckshee K, Pande J N
Deptt. of Obs & Gynae, Sir Salimullah Medical College, New Delhi, India.
Bangladesh Med Res Counc Bull. 1996 Aug;22(2):51-9.
This prospective cross sectional study was conducted in a tertiary hospital in Northern India. The objective of the study was to investigate the utility of recording certain fetal biophysical variables at or near term in high risk pregnancy for predicting the fetal outcome. A fetal biophysical profile score was used for predicting the outcome. The scoring system utilized following variables: non stress test, fetal breathing movement, fetal movement, fetal tone and amniotic fluid volume. One hundred and fifty four pregnant women attending a high risk pregnancy clinic were consecutively included in the study. At a cut off score < or = 4, sensitivity of the scoring system was 12.5% and specificity 99.23%. At score < or = 8, corresponding figures were 70.83% and 91.53%. As compared to each individual variable, the positive predictive value for abnormal perinatal outcome improved considerably after combining all the variables. The negative predictive value for normal perinatal outcome did not improve. Though biophysical profile scoring is used as a valuable adjunct in caring high risk fetuses, a simple and more practical screening test should be sought for. The cost-benefit analysis of such tests should also be performed.
这项前瞻性横断面研究在印度北部的一家三级医院进行。该研究的目的是调查在高危妊娠足月或接近足月时记录某些胎儿生物物理变量对预测胎儿结局的效用。使用胎儿生物物理评分来预测结局。评分系统采用以下变量：无应激试验、胎儿呼吸运动、胎动、胎儿肌张力和羊水量。154名前往高危妊娠门诊的孕妇被连续纳入研究。在临界值≤4分时，评分系统的敏感性为12.5%，特异性为99.23%。在≤8分时，相应数字分别为70.83%和91.53%。与每个单独变量相比，将所有变量组合后围产期异常结局的阳性预测值有显著提高。围产期正常结局的阴性预测值没有改善。虽然生物物理评分在照顾高危胎儿方面是一项有价值的辅助手段，但应寻求一种更简单、更实用的筛查试验。还应对此类试验进行成本效益分析。
