Chamiso D
Department of Obstetrics and Gynaecology, Addis Ababa University, Faculty of Medicine, Ethiopia.
East Afr Med J. 1996 Dec;73(12):805-9.
Between January 1993 and January 1995, a prospective case-control hospital-based study was done in ninety-two HIV seropositive and 173 HIV seronegative mothers for pregnancy outcome and complications associated with the pregnancy in Gandhi Memorial Hospital, Addis Ababa, Ethiopia. The serostatus and seroconversion in the children born to the seropositive women was also assessed. The study showed that there was a significant difference in birthweight (p < 0.001), puerperal infections (p < 0.0001), duration of pregnancy (p < 0.001), and fifth minute APGAR score (p < 0.001) in the two groups of the study population. The study further indicated that the seroprevalence in the pregnant women was 20.4% and vertical transmission rate at 18 months was 68.5%. From the study one can conclude that HIV seropositivity adversely affects pregnancy out come.
1993年1月至1995年1月期间，在埃塞俄比亚亚的斯亚贝巴甘地纪念医院，对92名HIV血清反应阳性和173名HIV血清反应阴性的母亲进行了一项基于医院的前瞻性病例对照研究，以了解妊娠结局及与妊娠相关的并发症情况。同时，还评估了血清反应阳性女性所生孩子的血清状态和血清转化情况。研究表明，在研究人群的两组中，出生体重（p < 0.001）、产褥期感染（p < 0.0001）、妊娠期（p < 0.001）和出生后五分钟阿氏评分（p < 0.001）存在显著差异。该研究进一步表明，孕妇中的血清阳性率为20.4%，18个月时的垂直传播率为68.5%。从该研究可以得出结论，HIV血清反应阳性会对妊娠结局产生不利影响。
