Satten G A
Division of HIV/AIDS (E-48), National Center for HIV, STD, and TB Prevention, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA.
Math Biosci. 1997 Apr 15;141(2):101-13. doi: 10.1016/s0025-5564(96)00185-x.
All blood donations in the United States are screened for human immunodeficiency virus (HIV), the virus that causes AIDS; in spite of this, potentially infectious donations are still made by donors who are infectious but have not yet developed detectable HIV antibodies. A steady-state model for blood donations is used to calculate the expected number of potentially infectious blood donations made by repeat blood donors in a specified time interval. The expected number of potentially infectious donations made by each infectious blood donor who subsequently becomes HIV positive is calculated, and estimators of this quantity are presented. The relative risks due to donations from repeat and first-time donors is discussed. Estimates of the proportion of all blood donations made at 19 American Red Cross regional blood centers that are potentially infectious are presented.
在美国，所有献血都要进行人类免疫缺陷病毒（HIV，即导致艾滋病的病毒）筛查；尽管如此，仍有一些具有潜在传染性的献血是由已感染但尚未产生可检测到的HIV抗体的献血者提供的。一种献血的稳态模型用于计算在特定时间间隔内重复献血者所献具有潜在传染性血液的预期数量。计算了随后检测出HIV呈阳性的每个感染性献血者所献具有潜在传染性血液的预期数量，并给出了该数量的估计值。讨论了重复献血者和首次献血者献血造成的相对风险。给出了美国红十字会19个地区血液中心所献全部血液中具有潜在传染性血液所占比例的估计值。
