艾滋病与新冠：两场大流行的故事及统计学家的角色
AIDS and COVID: A tale of two pandemics and the role of statisticians.
机构信息
Department of Biostatistics, Epidemiology and Informatics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
出版信息
Stat Med. 2021 May 20;40(11):2499-2510. doi: 10.1002/sim.8936.
Abstract
The world has experienced three global pandemics over the last half-century: HIV/AIDS, H1N1, and COVID-19. HIV/AIDS and COVID-19 are still with us and have wrought extensive havoc worldwide. There are many differences between these two infections and their global impacts, but one thing they have in common is the mobilization of scientific resources to both understand the infection and develop ways to combat it. As was the case with HIV, statisticians have been in the forefront of scientists working to understand transmission dynamics and the natural history of infection, determine prognostic factors for severe disease, and develop optimal study designs to assess therapeutics and vaccines.
摘要
在过去的半个世纪里，世界经历了三次全球大流行：艾滋病病毒/艾滋病、H1N1 和 COVID-19。艾滋病病毒/艾滋病和 COVID-19仍然存在，并在全球范围内造成了广泛的破坏。这两种感染及其全球影响有许多不同之处，但它们有一个共同点，那就是动员科学资源来了解感染并开发对抗它的方法。就像艾滋病病毒一样，统计学家一直处于科学家的前沿，努力了解传播动态和感染的自然史，确定严重疾病的预后因素，并制定最佳研究设计来评估治疗方法和疫苗。
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