Huin E, Tan K P
Department of Diagnostic Radiology, Singapore General Hospital, Singapore.
Singapore Med J. 1996 Dec;37(6):622-6.
Central pontine and extrapontine myelinolysis is a distinctive clinical syndrome and has characteristic CT and MR features. We describe two patients who presented with nasopharyngeal carcinoma, severe hyponatremia, and had quick correction of hyponatremia. Low T1 and high T2 signal alterations were seen in the basal ganglia and caudate nuclei in both patients whilst one of them had concommitant ventrolateral thalami and central pontine region involvement. Neurologic recovery was good in one case, and initially seen in the other patient before death resulted from septicaemia. Peripheral enhancement of the basal ganglia and caudate nuclei was seen in one patient, which we believe is a new feature.
中央桥脑及桥外髓鞘溶解症是一种独特的临床综合征，具有特征性的CT和MR表现。我们描述了两名患有鼻咽癌、严重低钠血症且低钠血症迅速纠正的患者。两名患者的基底节和尾状核均出现低T1和高T2信号改变，其中一名患者同时累及丘脑腹外侧和中央桥脑区域。一例患者神经功能恢复良好，另一例患者在死于败血症之前最初也有神经功能恢复。在一名患者中观察到基底节和尾状核的外周强化，我们认为这是一个新特征。
