Alleman Anthony M
Department of Radiological Sciences, The University of Oklahoma Health Sciences Center, Oklahoma City, OK.
Semin Ultrasound CT MR. 2014 Apr;35(2):153-9. doi: 10.1053/j.sult.2013.09.009. Epub 2013 Sep 28.
Osmotic demyelination syndrome (ODS) refers to central pontine myelinolysis and extrapontine myelinolysis. These disorders are characterized by insults to regions of the brain with anatomical features predisposing white matter tracts to myelin injury in the setting of osmotic disturbances and their attempted correction. Occurring independently or in combination, central pontine myelinolysis and extrapontine myelinolysis share a characteristic timing of onset, but distinct clinical features. Imaging features demonstrate characteristic findings that suggest ODS, but must be correlated with clinical features. Once thought to be universally devastating, ODS currently can have a variable clinical outcome.
渗透性脱髓鞘综合征（ODS）指的是脑桥中央髓鞘溶解症和脑桥外髓鞘溶解症。这些病症的特点是在渗透性紊乱及其纠正过程中，对具有使白质束易发生髓鞘损伤的解剖学特征的脑区造成损害。脑桥中央髓鞘溶解症和脑桥外髓鞘溶解症可单独发生或合并出现，具有共同的特征性发病时间，但临床特征不同。影像学特征显示出提示ODS的特征性表现，但必须与临床特征相关联。ODS曾被认为普遍具有毁灭性，但目前其临床结局可能有所不同。
