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[对用人胚肺细胞与小鼠细胞共培养的人类胚胎肺细胞中肿瘤病毒的常见和“最小形式”的电子显微镜研究] (注:原文中“cataminated”可能有误,推测应为“co-cultivated”之类的词,这里按给定原文翻译)

[Electron microscopic study of the usual and "minimal forms" of oncornaviruses in human embryonic lung cells cataminated with mouse cells].

作者信息

Bykovskiĭ A F, Klitsunova N V, Glinskikh N P

出版信息

Vopr Virusol. 1977(1):76-82.

PMID:910442
Abstract

Electron microscopic examinations of KLChKM (human embryo cells spontaneously contaminated with mouse cells) cell cultures revealed extracellular oncornaviruses of A and C types and intracisternal virions of A type which in their submicroscopical organization and morphogenesis were identical to oncornaviruses of mouse L cells. Also "minimal forms" (MiF) of oncornaviruses of A and C types the diameter of which was 30--70 nm were found. MiF of oncornaviruses were found to be formed in the process of budding through the cytoplasmic membrane or membranes of intracellular vacuoles.

摘要

对KLChKM(自发被小鼠细胞污染的人胚胎细胞)细胞培养物进行的电子显微镜检查发现了A和C型细胞外肿瘤病毒以及A型核内体病毒粒子,它们在亚微观结构和形态发生方面与小鼠L细胞的肿瘤病毒相同。还发现了直径为30 - 70纳米的A和C型肿瘤病毒的“最小形式”(MiF)。肿瘤病毒的MiF被发现是通过细胞质膜或细胞内液泡膜出芽的过程形成的。

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