Patterson-Kane J C, Wilson A M, Firth E C, Parry D A, Goodship A E
Department of Veterinary Clinical Sciences, Massey University, Palmerston North, New Zealand.
Equine Vet J. 1997 Mar;29(2):121-5. doi: 10.1111/j.2042-3306.1997.tb01653.x.
This study was undertaken to test the hypothesis that collagen fibrils, the submicroscopic units of strength in tendon, would hypertrophy in response to a specific defined training programme. Fibril diameters were measured in central and peripheral regions of superficial digital flexor tendon (SDFT) samples from five 18-month-old horses which underwent a subsequent 18 month training programme and 6 age- and sex-matched controls. Central region fibrils from the trained horses had a mass-average diameter (MAD) of 105.3 nm, which was significantly lower (P < 0.01) than that of 131.7 nm for the same region in the control horses. This reduction in fibril diameter in the region of tendon which is predisposed to injury was interpreted as evidence of microtrauma, as it implies the region is weakened by the training regimen. Repeated episodes of microtrauma may accumulate and eventually result in degenerative lesions and clinical tendonitis.
肌腱中作为强度亚微观单位的胶原纤维会对特定的既定训练计划产生肥大反应。对五匹18月龄马匹的指浅屈肌腱（SDFT）样本的中央和周边区域的纤维直径进行了测量，这些马匹随后接受了为期18个月的训练计划，并设置了6个年龄和性别匹配的对照组。训练马匹的中央区域纤维的质量平均直径（MAD）为105.3纳米，显著低于（P < 0.01）对照马匹同一区域的131.7纳米。在易受伤的肌腱区域，纤维直径的这种减小被解释为微创伤的证据，因为这意味着该区域因训练方案而变弱。反复的微创伤事件可能会累积，最终导致退行性病变和临床肌腱炎。
