Yamamoto M, Maesima E, Yamada Y, Yukawa S, Maeda T
Third Department of Internal Medicine, Wakayama Medical College.
Nihon Rinsho Meneki Gakkai Kaishi. 1997 Feb;20(1):67-72. doi: 10.2177/jsci.20.67.
We reported a 26-year-old female who had experienced 2 miscarriages associated with a possible cause of antiphospholipid antibody. She consulted to Kainan Municipal Hospital with major complaints of miscarriages and positive antiphospholipid antibody. No evidence of obstetric disorder was apparent and routine haematological parameters were normal. Serological studies and clinical evidence did not show SLE. While biologically false positive (reaction of serological test for syphilis) and lupus anticoagulant was negative, IgG anticardiolipin antibody was positive. She was diagnosed as possible antiphospholipid antibody syndrome based on positive anticardiolipin antibody and the history of miscarriages. In 1993, she was started on prednisolone and aspirin therapy; antiphospholipid antibody returned to negative. Treatment with prednisolone (7.5 mg/day) and aspirin (40 mg/day) was continued. She was able to be pregnant. She gave birth successfully at our hospital in August 1995. She and her newborn showed no abnormalities.
我们报告了一名26岁女性，她经历了2次流产，可能原因是抗磷脂抗体。她因流产及抗磷脂抗体阳性的主要诉求就诊于海南市立医院。未发现明显的产科疾病证据，常规血液学参数正常。血清学研究及临床证据未显示系统性红斑狼疮（SLE）。虽然梅毒血清学试验生物学假阳性及狼疮抗凝物为阴性，但IgG抗心磷脂抗体呈阳性。基于抗心磷脂抗体阳性及流产史，她被诊断为可能的抗磷脂抗体综合征。1993年，她开始接受泼尼松龙和阿司匹林治疗；抗磷脂抗体转阴。继续使用泼尼松龙（7.5毫克/天）和阿司匹林（40毫克/天）治疗。她成功怀孕。1995年8月在我院顺利分娩。她和新生儿均无异常。
