Verdon M E
Hunterdon Medical Center Family Practice Residency Program, Flemington, New Jersey, USA.
Am Fam Physician. 1997 Apr;55(5):1813-6, 1819, 1822.
Human papillomavirus (HPV) infects epithelial cells at a variety of anatomic sites. Of the more than 80 types of this virus, approximately one third infect genital tissue. Genital infection can be clinical (warts), subclinical (abnormal Papanicolaou [Pap] smears or lesions visible only with magnification and application of acetic acid) or latent (infection with apparently normal tissue). Recent research has revealed a clear association between genital warts and HPV types 6 and 11, and between cervical cancer and HPV types 16, 18 and others. Women with genital warts who have normal Pap smears do not need colposcopy. All available therapies are suboptimal because HPV is not eradicated by treatment. However, the active disease expression can be eliminated by treatment. The approach to treatment will depend on each patient's personal characteristics and preferences.
人乳头瘤病毒（HPV）可感染多种解剖部位的上皮细胞。在该病毒的80多种类型中，约三分之一会感染生殖组织。生殖器感染可为临床型（疣）、亚临床型（巴氏涂片异常或仅在放大及应用醋酸后可见的病变）或潜伏型（感染表面正常的组织）。最近的研究表明，生殖器疣与6型和11型HPV之间、宫颈癌与16型、18型及其他HPV类型之间存在明确关联。巴氏涂片正常的生殖器疣女性无需进行阴道镜检查。由于治疗无法根除HPV，所有现有的治疗方法都并非最佳。然而，治疗可消除疾病的活跃表现。治疗方法将取决于每位患者的个人特征和偏好。
