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一项关于温度依赖性前庭电位的研究:持久热刺激和氨基糖苷类药物的影响。

A study on temperature dependent vestibular potential: effect of long lasting thermal stimulus and aminoglycoside agent.

作者信息

Suzuki M, Kadir A, Takamoto M, Hayashi N, Harada Y

机构信息

Department of Otolaryngology, Hiroshima University, School of Medicine, Japan.

出版信息

Acta Otolaryngol. 1997 Mar;117(2):219-21. doi: 10.3109/00016489709117774.

DOI:10.3109/00016489709117774
PMID:9105453
Abstract

Effect of temperature changes on the vestibular receptor was studied using isolated posterior semicircular canals (PSC) of bull frogs. Cupula was removed from the crista. PSC was placed in the inner compartment of the double chamber. Warm or cool water was filled in the outer compartment to change the temperature of the inner compartment. Changes of the spontaneous discharge were recorded from the ampullary nerve. When cooled, the discharge temporarily increased, followed by a gradual decrease. When warmed, it temporarily decreased and then increased, forming response curves of a mirror image. After addition of streptomycin, the temperature dependent response disappeared. These results suggest that the semicircular canal receptor is activated by direct temperature effects.

摘要

利用牛蛙分离的后半规管(PSC)研究了温度变化对前庭感受器的影响。从嵴顶去除了壶腹帽。将PSC置于双室的内室中。在外室中注入温水或冷水以改变内室的温度。从壶腹神经记录自发放电的变化。冷却时,放电暂时增加,随后逐渐减少。加热时,放电暂时减少然后增加,形成镜像的反应曲线。加入链霉素后,温度依赖性反应消失。这些结果表明,半规管感受器由直接的温度效应激活。

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