Lewis B E, Grassman E D, Wrona L, Rangel Y
Columbus Hospital, Chicago, IL 60614, USA.
Blood Coagul Fibrinolysis. 1997 Jan;8(1):54-8. doi: 10.1097/00001721-199701000-00009.
We describe a case of a 70-year-old male who underwent coronary artery bypass surgery which was complicated by multiple thrombotic events associated with HIT. The thrombotic events were treated with intravenous argatroban (Novastan). During the hospitalization the patient was found to require percutaneous bilateral renal artery revascularization for acute renal failure. The revascularization procedure was successfully accomplished with a high dose argatroban regimen. We present our report of a successful anticoagulation strategy during a peripheral intervention in a patient with HIT and the laboratory data which support this strategy.
我们描述了一例70岁男性患者，该患者接受了冠状动脉搭桥手术，术后并发了多起与肝素诱导的血小板减少症（HIT）相关的血栓形成事件。这些血栓形成事件采用静脉注射阿加曲班（诺瓦斯坦）进行治疗。住院期间，发现该患者因急性肾衰竭需要进行经皮双侧肾动脉血运重建术。通过高剂量阿加曲班方案成功完成了血运重建手术。我们报告了在一名HIT患者进行外周介入治疗期间成功的抗凝策略以及支持该策略的实验室数据。
