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首例使用阿加曲班抗凝成功植入颈动脉支架治疗肝素诱导的血小板减少症和血栓形成综合征患者:病例报告

The first report of successful carotid stent implant using argatroban anticoagulation in a patient with heparin-induced thrombocytopenia and thrombosis syndrome: a case report.

作者信息

Lewis B E, Rangel Y, Fareed J

机构信息

Section of Cardiology, Columbus Hospital, Chicago, Illinois, USA.

出版信息

Angiology. 1998 Jan;49(1):61-7. doi: 10.1177/000331979804900108.

DOI:10.1177/000331979804900108
PMID:9456166
Abstract

We report the first successful carotid stent implant in a patient with heparin-induced thrombocytopenia and thrombosis syndrome who presented with recurrent neurologic deficits secondary to severe carotid stenosis. Argatroban anticoagulation was used for the carotid stent deployment. We also present laboratory data that document effective procedural anticoagulation.

摘要

我们报告了首例成功为一名患有肝素诱导的血小板减少和血栓形成综合征且因严重颈动脉狭窄继发反复神经功能缺损的患者植入颈动脉支架的病例。阿加曲班抗凝用于颈动脉支架置入术。我们还展示了记录有效术中抗凝的实验室数据。

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The first report of successful carotid stent implant using argatroban anticoagulation in a patient with heparin-induced thrombocytopenia and thrombosis syndrome: a case report.首例使用阿加曲班抗凝成功植入颈动脉支架治疗肝素诱导的血小板减少症和血栓形成综合征患者:病例报告
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[Heparin-induced thrombocytopenia].
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引用本文的文献

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Safety of argatroban to address heparin hypersensitivity in open and interventional carotid procedures.阿加曲班用于开放性和介入性颈动脉手术中处理肝素过敏的安全性。
Surg Neurol Int. 2025 Aug 1;16:320. doi: 10.25259/SNI_560_2025. eCollection 2025.
2
The use of anticoagulation in pediatric cardiac disease.抗凝治疗在小儿心脏疾病中的应用。
Images Paediatr Cardiol. 2003 Jul;5(3):1-35.
3
Benefit-risk assessment of treatments for heparin-induced thrombocytopenia.肝素诱导的血小板减少症治疗的获益-风险评估
Drug Saf. 2003;26(9):625-41. doi: 10.2165/00002018-200326090-00003.
4
A synopsis of the clinical uses of argatroban.阿加曲班的临床应用概述。
J Thromb Thrombolysis. 2001 Oct;12(2):141-9. doi: 10.1023/a:1012919404290.
5
Argatroban.阿加曲班
Drugs. 2001;61(4):515-22; discussion 523-4. doi: 10.2165/00003495-200161040-00005.