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双相抑郁、单相抑郁和心境恶劣障碍中焦虑症共病的患病率。

Prevalence of anxiety disorders comorbidity in bipolar depression, unipolar depression and dysthymia.

作者信息

Pini S, Cassano G B, Simonini E, Savino M, Russo A, Montgomery S A

机构信息

Institute of Psychiatry, University of Verona, Ospedale Policlinico, Italy.

出版信息

J Affect Disord. 1997 Feb;42(2-3):145-53. doi: 10.1016/s0165-0327(96)01405-x.

Abstract

Eighty-seven patients with current episode of depression were assessed by the SCID-P and subdivided in bipolar depressives (N = 24), unipolar depressives (n = 38) and dysthymics (n = 25). Anxiety disorders comorbidity in these three groups was investigated by means of the SCID-P. Panic disorder comorbidity was found in 36.8% of bipolar depressives, 31.4% of unipolar depressives and 13% of dysthymics. Prevalence of obsessive-compulsive disorder was 21.1% in bipolars, 14.3% in unipolars and 8.7% in dysthymics. Generalized anxiety disorder resulted in being much more associated with dysthymia (65.2%) than with bipolar (31.6%) or unipolar depression (37.1%). Social phobia comorbidity was exhibited mainly by unipolars (11.4%), while no cases were detected in the bipolar group. Odds ratios revealed that generalized anxiety disorder is significantly more likely to co-occur with dysthymia. Panic disorder showed a higher trend to be associated with bipolar and unipolar depression. Social phobia was more frequent among unipolar depression.

摘要

87例当前患有抑郁症的患者接受了情感障碍定式临床检查问卷(SCID-P)评估,并被分为双相抑郁组(N = 24)、单相抑郁组(n = 38)和恶劣心境组(n = 25)。通过SCID-P对这三组中的焦虑症共病情况进行了调查。双相抑郁组中惊恐障碍共病率为36.8%,单相抑郁组为31.4%,恶劣心境组为13%。双相障碍患者中强迫症患病率为21.1%,单相抑郁患者中为14.3%,恶劣心境患者中为8.7%。结果显示,广泛性焦虑症与恶劣心境(65.2%)的关联程度远高于双相抑郁(31.6%)或单相抑郁(37.1%)。社交恐惧症共病主要出现在单相抑郁组(11.4%),而双相障碍组未检测到病例。优势比显示,广泛性焦虑症与恶劣心境共病的可能性显著更高。惊恐障碍与双相和单相抑郁的关联趋势更高。社交恐惧症在单相抑郁中更为常见。

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