Hoeffel C, Heldt N, Chelle C, Claudon M, Hoeffel J C
Department of Radiology, Hôpital Jeanne d'Arc, Toul, France.
Acta Neurol Belg. 1997 Mar;97(1):45-9.
We describe a unique case of an intra-diploic epidermoid cyst of the parietal and occipital right bone in a 43 year-old man. The tumor remained quiescent for 12 years and then spontaneously showed malignant changes with intra-cerebral involvement. Fatal outcome occurred one year after surgery, radiation therapy and chemotherapy because of a recurrence. Malignant transformation of the epithelium in epidermoid cyst is very rare. Our case is the first one where this transformation occurred spontaneously without previous surgery.
我们描述了一例43岁男性右侧顶骨和枕骨板障内表皮样囊肿的独特病例。该肿瘤静止12年后，自发出现恶性变并累及脑内。在手术、放疗和化疗一年后，因复发导致死亡。表皮样囊肿上皮的恶性转化非常罕见。我们的病例是首例未经手术而自发发生这种转化的情况。
