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通过D2O的2H固态核磁共振测定L(α)相和L(β')相中DMPC的水合作用。

Determination of DMPC hydration in the L(alpha) and L(beta') phases by 2H solid state NMR of D2O.

作者信息

Faure C, Bonakdar L, Dufourc E J

机构信息

Centre de Recherche Paul Pascal, CNRS, Pessac, France.

出版信息

FEBS Lett. 1997 Apr 1;405(3):263-6. doi: 10.1016/s0014-5793(97)00201-9.

DOI:10.1016/s0014-5793(97)00201-9
PMID:9108301
Abstract

The number of water molecules bound to the dimyristoylphosphatidylcholine (DMPC) interface was investigated both in the fluid (L(alpha)) and gel (L(beta')) phases by solid state deuterium NMR of D2O. We determined that each DMPC molecule binds 9.7 +/- 0.5 and less than 4.3 +/- 0.5 D2O in the fluid and gel phases respectively. These results are accounted for by considering the number of DMPC binding sites as well as the molecular organization in each phase.

摘要

通过对重水(D2O)进行固态氘核磁共振,研究了在流体(L(α))相和凝胶(L(β'))相中与二肉豆蔻酰磷脂酰胆碱(DMPC)界面结合的水分子数量。我们确定,在流体相和凝胶相中,每个DMPC分子分别结合9.7±0.5个和少于4.3±0.5个D2O分子。这些结果可以通过考虑DMPC结合位点的数量以及各相中的分子组织来解释。

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