Lack of emergence of genotypic resistance to stavudine after 2 years of monotherapy.

作者信息

Soriano V, Dietrich U, Villalba N, Immelmann A, Gil-Aguado A, Echevarría S, Clotet B, Ocaña I, Santamaría J M, Bouza E, Barona V, Gatell J M, González-Lahoz J

出版信息

AIDS. 1997 Apr;11(5):696-7.

PMID:9108961

Abstract

摘要

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Lack of emergence of genotypic resistance to stavudine after 2 years of monotherapy.

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引用本文的文献

ATP-dependent removal of nucleoside reverse transcriptase inhibitors by human immunodeficiency virus type 1 reverse transcriptase.1型人类免疫缺陷病毒逆转录酶通过ATP依赖性方式去除核苷类逆转录酶抑制剂

Antimicrob Agents Chemother. 2002 Jul;46(7):2179-84. doi: 10.1128/AAC.46.7.2179-2184.2002.

Antiretroviral Drug Resistance in HIV-1.HIV-1中的抗逆转录病毒药物耐药性

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Differential removal of thymidine nucleotide analogues from blocked DNA chains by human immunodeficiency virus reverse transcriptase in the presence of physiological concentrations of 2'-deoxynucleoside triphosphates.在生理浓度的2'-脱氧核苷三磷酸存在的情况下，人类免疫缺陷病毒逆转录酶对受阻DNA链中胸苷酸类似物的差异去除。

Antimicrob Agents Chemother. 2000 Dec;44(12):3465-72. doi: 10.1128/AAC.44.12.3465-3472.2000.

Stavudine: an update of its use in the treatment of HIV infection.司他夫定：其在治疗HIV感染方面应用的最新情况。

Drugs. 1999 Nov;58(5):919-49. doi: 10.2165/00003495-199958050-00012.

A family of insertion mutations between codons 67 and 70 of human immunodeficiency virus type 1 reverse transcriptase confer multinucleoside analog resistance.人类免疫缺陷病毒1型逆转录酶第67和70密码子之间的插入突变家族赋予多核苷类似物抗性。

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