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使用与自体骨移植相关的可吸收和不可吸收膜治疗牙种植体周围的裂开和开窗:一项对比临床研究。

Treatment of dehiscences and fenestrations around dental implants using resorbable and nonresorbable membranes associated with bone autografts: a comparative clinical study.

作者信息

Simion M, Misitano U, Gionso L, Salvato A

机构信息

Department of Dentistry, University of Milan, San Raffaele Hospital, Italy.

出版信息

Int J Oral Maxillofac Implants. 1997 Mar-Apr;12(2):159-67.

PMID:9109265
Abstract

This study was carried out to evaluate the efficacy of poly(lactic acid) and poly(glycolic acid) (PLA/PGA) resorbable membranes in conjunction with autogenous bone grafts when used for the treatment of implant dehiscences and/or fenestrations. Nine patients with a total of 18 implants participated. Nine implants were associated with dehiscences, and 9 with fenestrations; 16 implants were in the maxilla, and 2 in the mandible. Nine defects were treated with PLA/PGA membranes (test group), and the nine were treated with expanded polytetrafluoroethylene (e-PTFE) membranes (control group). Second-stage surgery was performed after 6 to 7 months of healing. Overall results of the regenerative therapy of the 18 defects showed a highly significant (P < .001) defect reduction, with a 93.38% (SD = 15.88) bone fill. A slightly higher percentage of bone fill was found in the e-PTFE group (98.20%) than in the PLA/PGA group (88.56%), but the difference was not statistically significant (P = .207). This study demonstrated that resorbable PLA/PGA membranes can be equally effective as e-PTFE in the treatment of implant dehiscences and fenestrations when associated with autogenous bone chips.

摘要

本研究旨在评估聚乳酸与聚乙醇酸(PLA/PGA)可吸收膜联合自体骨移植用于治疗种植体裂开和/或骨窗时的疗效。9例患者共18颗种植体参与研究。9颗种植体伴有裂开,9颗伴有骨窗;16颗种植体在上颌骨,2颗在下颌骨。9处缺损采用PLA/PGA膜治疗(试验组),9处采用膨体聚四氟乙烯(e-PTFE)膜治疗(对照组)。愈合6至7个月后进行二期手术。18处缺损再生治疗的总体结果显示,骨缺损减少非常显著(P <.001),骨填充率为93.38%(标准差 = 15.88)。e-PTFE组的骨填充率(98.20%)略高于PLA/PGA组(88.56%),但差异无统计学意义(P = 0.207)。本研究表明,可吸收的PLA/PGA膜在与自体骨屑联合使用时,治疗种植体裂开和骨窗的效果与e-PTFE相当。

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