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通过人为关联的神经元活动破坏视觉皮层中的方向调谐。

Disruption of orientation tuning in visual cortex by artificially correlated neuronal activity.

作者信息

Weliky M, Katz L C

机构信息

Howard Hughes Medical Institute and Department of Neurobiology, Duke University School of Medicine, Durham, North Carolina 27710, USA.

出版信息

Nature. 1997 Apr 17;386(6626):680-5. doi: 10.1038/386680a0.

DOI:10.1038/386680a0
PMID:9109486
Abstract

In the primary visual cortex, the development of orientation selectivity is influenced by patterns of neural activity. The introduction of artificially correlated activity into the visual pathway (through synchronous activation of retinal ganglion cell axons in the optic nerve) substantially weakens the orientation selectivity of neurons in superficial and deep cortical layers. This is consistent with activity having an instructive role in shaping cortical neuron receptive field tuning properties.

摘要

在初级视觉皮层中,方向选择性的发展受神经活动模式的影响。将人工关联的活动引入视觉通路(通过同步激活视神经中的视网膜神经节细胞轴突)会显著削弱皮层浅层和深层神经元的方向选择性。这与活动在塑造皮层神经元感受野调谐特性方面具有指导作用是一致的。

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